Smith, Lisa, Dr

Dr Lisa Smith

School of Biosciences

Senior Lecturer

lisa.m.smith@sheffield.ac.uk

C34a, Alfred Denny Building

Full contact details

Dr Lisa Smith
School of Biosciences
C34a
Alfred Denny Building
Western Bank
Sheffield
S10 2TN

Profile

Lecturer, School of Biosciences, University of Sheffield, UK (2013-present)
Postdoctoral Fellow, Department of Molecular Biology, Max Planck Institute for Developmental Biology, Germany (2007-2013)
PhD Student, The Sainsbury Laboratory, Norwich, UK (2002-2006)
BSc (Hons), The University of Queensland, Australia (1998-2001)

�鶹��Ƶ interests

The Smith lab is primarily focused plant reproduction. We study a group of receptor kinases that detect signals coming either from other plant cells or from the surrounding environment. Their functions help the cell and plant develop and respond appropriately according to the wider environment. Our research is currently focussed on the function of malectin-like domain receptor kinases in fertilisation, where the male and female gametes exchange signals. This research on reproduction is in collaboration with Andrew Fleming and Sam Amsbury at the University of Sheffield as well as external collaborators.

A second line of research in the lab examines the developmental roles of malectin domain kinesins. Kinesins are motor proteins that can move around the cell using the cytoskeleton. Kinesins are particularly important in plant cell division where they can restructure the cytoskeleton and shift organelles. In work funded by The Leverhulme Trust, we aim to understand the function of malectin domain kinesins in reproduction and cell division.

I remain interested in diverse areas of plant molecular biology such as natural variation, epigenetics and transposable elements. Together with Jurriaan Ton and Stephen Rolfe’s labs and external collaborators, I study the long-term effects of biotic stress on heritable variations, and the potential to use transgenerational inherited resistance to make better crops.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Yao N, Zhang Z, Yu L, Hazarika R, Yu C, Jang H, Smith LM, Ton J, Liu L, Stachowicz JJ , Reusch TBH et al (2023) . Science, 381(6665), 1440-1445.
Baillie AL, Sloan J, Qu L-J & Smith LM (2023) . Trends in Plant Science.
Naish M, Alonge M, Wlodzimierz P, Tock AJ, Abramson BW, Schmücker A, Mandáková T, Jamge B, Lambing C, Kuo P , Yelina N et al (2021) . Science, 374(6569).
Galindo-Trigo S, Blanco-Touriñán N, DeFalco TA, Wells ES, Gray JE, Zipfel C & Smith LM (2020) . EMBO Reports, 21(2).
Galindo-Trigo S, Grand TM, Voigt CA & Smith LM (2020) . J Exp Bot, 71(6), 1828-1841.
Wilkinson SW, Magerøy MH, López Sánchez A, Smith LM, Furci L, Cotton TEA, Krokene P & Ton J (2019) . Annual Review of Phytopathology, 57(1), 505-529.
Stassen JHM, López A, Jain R, Pascual-Pardo D, Luna E, Smith LM & Ton J (2018) . Scientific Reports, 8(1).
López Sánchez A, H M Stassen J, Furci L, Smith LM & Ton J (2016) . Plant Journal, 88(3), 361-374.
Galindo-Trigo S, Gray JE & Smith LM (2016) . Frontiers in Plant Science, 7(AUG2016).
Smith LM, Burbano HA, Wang X, Fitz J, Wang G, Ural-Blimke Y & Weigel D (2015) . The Plant Journal, 81(4), 597-610.
Wang X, Weigel D & Smith LM (2013) . PLoS Genet, 9(2), e1003255.
Smith LM, Hartmann L, Drewe P, Bohnert R, Kahles A, Lanz C & Rätsch G (2012) . RNA Biol, 9(5), 596-609.
Smith LM, Bomblies K & Weigel D (2011) . PLoS Genet, 7(7), e1002164.
Hollister JD, Smith LM, Guo YL, Ott F, Weigel D & Gaut BS (2011) . Proceedings of the National Academy of Sciences of the United States of America, 108(6), 2322-2327.

All publications

Journal articles

Grand TM, Pitman JK, Williams AL, Smith LM & Fleming AJ (2025) . Plant Direct, 9(4).
Yao N, Zhang Z, Yu L, Hazarika R, Yu C, Jang H, Smith LM, Ton J, Liu L, Stachowicz JJ , Reusch TBH et al (2023) . Science, 381(6665), 1440-1445.
Baillie AL, Sloan J, Qu L-J & Smith LM (2023) . Trends in Plant Science.
Sageman-Furnas K, Nurmi M, Contag M, Plötner B, Alseekh S, Wiszniewski A, Fernie AR, Smith LM & Laitinen RAE (2022) . Plant Cell Physiol.
Naish M, Alonge M, Wlodzimierz P, Tock AJ, Abramson BW, Schmücker A, Mandáková T, Jamge B, Lambing C, Kuo P , Yelina N et al (2021) . Science, 374(6569).
David R, Ng PQ, Smith LM & Searle IR (2021) . MicroPubl Biol, 2021.
Galindo-Trigo S, Blanco-Touriñán N, DeFalco TA, Wells ES, Gray JE, Zipfel C & Smith LM (2020) . EMBO Reports, 21(2).
Galindo-Trigo S, Grand TM, Voigt CA & Smith LM (2020) . J Exp Bot, 71(6), 1828-1841.
Cox N & Smith LM (2019) . Plant Physiology, 181(4), 1398-1400.
Smith LM (2019) . Plant Physiology, 181(2), 387-388.
Wilkinson SW, Magerøy MH, López Sánchez A, Smith LM, Furci L, Cotton TEA, Krokene P & Ton J (2019) . Annual Review of Phytopathology, 57(1), 505-529.
Cox N & Smith LM (2019) . Plant Physiology, 180(4), 1781-1783.
Smith LM (2019) . Plant Physiology, 180(1), 3-4.
Smith LM (2019) . Plant Physiology, 180(1), 7-9.
Stassen JHM, López A, Jain R, Pascual-Pardo D, Luna E, Smith LM & Ton J (2018) . Scientific Reports, 8(1).
Smith LM (2018) . Plant Physiology, 178(1), 7-8.
Smith L & Butler N (2018) . Plant Physiology, 177(2), 443-444.
Epihov DZ, Batterman SA, Hedin LO, Leake JR, Smith LM & Beerling DJ (2017) . Proceedings of the Royal Society B: Biological Sciences, 284(1860).
López Sánchez A, H M Stassen J, Furci L, Smith LM & Ton J (2016) . Plant Journal, 88(3), 361-374.
Galindo-Trigo S, Gray JE & Smith LM (2016) . Frontiers in Plant Science, 7(AUG2016).
Smith LM, Burbano HA, Wang X, Fitz J, Wang G, Ural-Blimke Y & Weigel D (2015) . The Plant Journal, 81(4), 597-610.
Koster T, Meyer K, Weinholdt C, Smith LM, Lummer M, Speth C, Grosse I, Weigel D & Staiger D (2014) . Nucleic Acids �鶹��Ƶ, 42(15), 9925-9936.
Todesco M, Kim S-T, Chae E, Bomblies K, Zaidem M, Smith LM, Weigel D & Laitinen RAE (2014) . PLoS Genetics, 10(7).
Slotte T, Hazzouri KM, Ågren JA, Koenig D, Maumus F, Guo YL, Steige K, Platts AE, Escobar JS, Newman LK , Wang W et al (2013) . Nature Genetics, 45(7), 831-835.
Wang X, Weigel D & Smith LM (2013) . PLoS Genet, 9(2), e1003255.
Smith LM, Hartmann L, Drewe P, Bohnert R, Kahles A, Lanz C & Rätsch G (2012) . RNA Biol, 9(5), 596-609.
Smith LM & Weigel D (2012) . EMBO J, 31(2), 249-250.
Smith LM, Bomblies K & Weigel D (2011) . PLoS Genet, 7(7), e1002164.
Schneeberger K, Ossowski S, Ott F, Klein JD, Wang X, Lanz C, Smith LM, Cao J, Fitz J, Warthmann N , Henz SR et al (2011) . Proc Natl Acad Sci U S A, 108(25), 10249-10254.
Hollister JD, Smith LM, Guo YL, Ott F, Weigel D & Gaut BS (2011) . Proceedings of the National Academy of Sciences of the United States of America, 108(6), 2322-2327.
Yelina NE, Smith LM, Jones AME, Patel K, Kelly KA & Baulcombe DC (2010) . Proceedings of the National Academy of Sciences of the United States of America, 107(31), 13948-13953.
Searle IR, Pontes O, Melnyk CW, Smith LM & Baulcombe DC (2010) . Genes and Development, 24(10), 986-991.
Fahlgren N, Jogdeo S, Kasschau KD, Sullivan CM, Chapman EJ, Laubinger S, Smith LM, Dasenko M, Givan SA, Weigel D & Carrington JC (2010) . Plant Cell, 22(4), 1074-1089.
Smith LM & Baulcombe DC (2007) . Plant Signaling and Behavior, 2(6), 501-502.
Bäurle I, Smith L, Baulcombe DC & Dean C (2007) . Science, 318(5847), 109-112.
Smith LM, Pontes O, Searle I, Yelina N, Yousafzai FK, Herr AJ, Pikaard CS & Baulcombe DC (2007) . Plant Cell, 19(5), 1507-1521.
Munro TP, Magee RJ, Kidd GJ, Carson JH, Barbarese E, Smith LM & Smith R (1999) . Journal of Biological Chemistry, 274(48), 34389-34395.
Cox N, Walker HJ, Pitman JK, Quick WP, Smith LM & Fleming AJ () .

Chapters

Smith LM (2015) In Pontes O & Jin H (Ed.), Nuclear Functions in Plant Transcription, Signaling and Development (pp. 133-164). New York: Springer.
Smith LM & Laitinen RAE (2015) In Laitinen RAE (Ed.), Molecular Mechanisms in Plant Adaptation (pp. 31-59). Hoboken, NJ, USA: John Wiley & Sons.

Conference proceedings papers

Stassen J, Furci L, Wilkinson SW, Lopez Sanchez A, Jain R, Smith LM & Ton J (2019) . Molecular Plant-Microbe Interactions, Vol. 32(10) (pp S1.17-S1.17). Glasgow, Scotland, 14 July 2019 - 18 July 2019.

Preprints

Grand TM, Pitman JK, Williams AL, Smith LM & Fleming AJ (2024) , Cold Spring Harbor Laboratory.
Zhang Z, Parker AH, Symeonidi A, Wilkinson SW, Stassen JHM, Smith LM, Ton J & Johannes F (2024) , Cold Spring Harbor Laboratory.
Yao N, Zhang Z, Yu L, Hazarika R, Yu C, Jang H, Smith LM, Ton J, Liu L, Stachowicz J , Reusch TBH et al (2023) , Cold Spring Harbor Laboratory.

�鶹��Ƶ group

Postdoctoral research associates

Dr Ellen Allwood: A plant-specific motor during cell division and seed development (funded by a Leverhulme Trust �鶹��Ƶ Project Grant)
Dr Jen Sloan: Peptide signalling during plant reproduction (BBSRC funded)
Dr Alice Baillie: Cell wall changes during plant reproduction (BBSRC funded)
Dr Louis Tirot (based in Jurriaan Ton’s group): Epigenetic regulation of plant development and defence (BBSRC IPA funded)

�鶹��Ƶ technician

Peijun Zhang (based in Jurriaan Ton’s group): Epigenetic regulation of plant development and defence.

PhD students

Adam Parker: Role of cytidine deaminase in (epi)genetic adaptation of the plant immune system. (BBSRC White Rose Mechanistic Biology DTP: primary supervisor Prof. Jurriaan Ton)

Teaching activities

I currently (2023-24) teach on the following modules:

APS11004 Plant Sciences: How to make a green planet
APS11009 Skills in Biology
BIS214 Plant, Cell and Environment
APS31005 Biological Laboratory �鶹��Ƶ - Applied Molecular Biology
APS355 Future Plants
L1 and L2 tutorials
BIS302 Literature Review
BIS303 �鶹��Ƶ Project
APS609 �鶹��Ƶ Project
APS610 Science Communication for �鶹��Ƶers
APS6610 Literature Review
APS6617 Scientific Skills and Project Management

I coordinate and am admissions tutor for our Masters of �鶹��Ƶ programme together with Prof. Steve Rolfe. I am also the PGT Year Tutor for the School of Biosciences.

�鶹��Ƶ

School of Biosciences

School of Biosciences

Dr Lisa Smith

Featured publications

Journal articles

All publications

Journal articles

Chapters

Conference proceedings papers

Preprints

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